01 / HIGH POTENCY DOSAGE
Exact 2 mg Active Assay
Each tablet contains Lorazepam IP 2 mg with strict active assay uniformity, rapid disintegration, and dissolution complying with Indian Pharmacopoeia standards.
Blessme · Anxiolytics & Sedatives
Lorazepam Tablets IP 2 mg - LORZIN-2
LORZIN-2 is a moderate-to-high potency oral formulation containing Lorazepam IP 2 mg by Blessme, Dellwich Lifescience LLP. Specifically indicated for severe generalized anxiety disorder, acute panic crises, debilitating anxiety-induced insomnia, and pre-operative tranquilization, providing robust GABAergic limbic suppression through direct Phase II glucuronidation.
High-Potency 2 mg Dose
Narcotic / Schedule H
Pan-India Supply
Product SpecificationsAbout Lorazepam Tablets IP 2 mg
About Lorazepam Tablets IP 2 mg
(LORZIN-2)
Comprehensive pharmaceutical specifications, active API monograph compliance, pharmacokinetic profiles, and 4x5x10 blister packaging details for LORZIN-2.
Blessme · Anxiolytic & Sedative
Lorazepam Tablets IP 2 mg - LORZIN-2
LORZIN-2 provides 2 mg Lorazepam per compressed tablet. Prescribed when higher anxiolytic potency is required to control severe panic episodes, intense autonomic agitation, or pre-procedural apprehension.
2 mg Lorazepam Delivers Powerful Limbic & Amygdala Tranquilization Direct Phase II Glucuronidation (No Active Metabolites) Intermediate Half-Life (10-20 Hours) Prevents Prolonged Hangover 4x5x10 Blister Strip Format for Tropical Protection Strict Indian Pharmacopoeia Quality Standards
- Product Brand Name
- LORZIN-2
- Active Pharmaceutical Ingredient
- Lorazepam IP 2 mgVerified IP
- Therapeutic Class
- Neuropsychiatric Anxiolytic & Sedative (Benzodiazepine)
- Dosage Form
- Oral Solid Compressed Tablet
- Strength Formulation
- 2 mg Lorazepam (Moderate-to-High Potency Formulation)
- Packaging Standard
- 4x5x10 Blister Strips (200 Tablets per Box)
- Regulatory Category
- Narcotic Drug
- Marketing Division
- Blessme · Neuro & Psychiatric Products
- Manufacturing Standard
- WHO-GMP & ISO 9001:2015 Certified Clean-Room Compression
- Storage Condition
- Store below 25°C in a dry place. Protect from light and moisture.
- Country of Origin
- India
Clinical & Commercial MonographLorazepam Tablet 2 mg & LORZIN-2
Lorazepam Tablet 2 mg & LORZIN-2
Complete Medical & Supply Guide
In-depth pharmacological evaluation of Lorazepam 2 mg tablets, marketed as LORZIN-2 by Blessme (Dellwich Lifescience LLP). Covers GABAergic receptor mechanisms, clinical advantages of direct glucuronidation, and pharmaceutical franchise availability across India.
What is LORZIN-2 (Lorazepam 2 mg)?
LORZIN-2 is a moderate-to-high potency oral benzodiazepine tablet formulated with 2 mg of pure Lorazepam IP. Formulated for clinical situations requiring higher GABAergic inhibition than standard 1 mg doses can afford.
In patients experiencing severe panic disorder with agoraphobia or acute psychomotor agitation, LORZIN-2 delivers rapid calming of autonomic hyperarousal, terminating racing thoughts, hyperventilation, and terror.
Clinical Uses & Evidence-Based Indications
Approved neurological and psychiatric indications for LORZIN-2 include:
- Severe Generalized Anxiety Disorder (GAD): Rapid suppression of intense anxiety failing low-dose therapy.
- Refractory Panic Disorder: Controls recurrent panic attacks and anticipatory dread.
- Severe Insomnia Secondary to Anxiety: Restores deep sleep in patients with severe night-time agitation.
- Preoperative Medication: Calms preoperative anxiety and creates beneficial anterograde amnesia.
- Acute Catatonia & Agitation: Manages catatonic stupor and acute psychomotor agitation under psychiatric protocol.
Neurochemical Mechanism of Action: GABAA Receptor Positive Modulation
Lorazepam 2 mg acts as a potent positive allosteric modulator at the GABAA receptor complex throughout the central nervous system.
By increasing the receptor’s affinity for gamma-aminobutyric acid (GABA), it facilitates the opening of ligand-gated chloride ion channels. The resulting cellular hyperpolarization suppresses excessive neuronal excitation in the amygdaloid complex, hippocampus, and cerebral cortex, delivering profound relief from psychic distress and muscular hypertonicity.
LORZIN-2 vs. LORZIN-1: Clinical Selection Criteria
How clinicians choose between the dosage strengths:
- LORZIN-1 (1 mg): Standard initial starting and maintenance dose for moderate generalized anxiety and mild sleep difficulty.
- LORZIN-2 (2 mg): Indicated for severe panic crises, acute psychiatric agitation, pre-operative sedation, or patients tolerant to 1 mg.
- Safety Profile: Both share direct glucuronidation metabolism without active intermediate metabolites.
Dosage Guidelines & Administration Method
LORZIN-2 must be taken strictly in accordance with medical advice:
- Severe Anxiety Dose: Typically 2 mg to 3 mg daily in divided doses (e.g., 1 mg morning, 1-2 mg night).
- Severe Insomnia: 2 mg taken at bedtime with water.
- Pre-Operative Sedation: 2 mg to 4 mg administered 1 to 2 hours before the procedure.
- Duration & Tapering: Prescribed for short durations (2-4 weeks); discontinue gradually under psychiatric supervision.
Critical Safety Warning - Schedule H / Narcotic Controlled Substance
LORZIN-2 contains Lorazepam, which carries potential for dependence and habit formation with prolonged therapy. Do not consume alcohol during therapy. Not recommended during pregnancy. Dispensed strictly against a valid registered medical prescription.
Quality & Production
Pharmaceutical Quality Assurance & Compliance
LORZIN-2 is manufactured in WHO-GMP certified facilities adhering to Schedule M protocols, ensuring micro-blend homogeneity, exact active content, and superior packaging stability.
02 / PROTECTIVE PACKAGING
Tropicalized 4x5x10 Blister
High-barrier blister packaging protects against ambient humidity and photodegradation, maintaining 36-month stability across all Indian climatic zones.
03 / PHARMACOPOEIA DOSSIERS
COA & Batch Testing Records
Every batch is verified through authenticated Certificates of Analysis (COA), HPLC active assay validation, and dissolution profiles adhering strictly to IP standards.
04 / WHO-GMP COMPLIANCE
Schedule M Manufacturing
Produced in state-of-the-art cleanroom manufacturing units in Gujarat adhering to automated compression, online check-weighing, and Good Laboratory Practices (GLP).
Clinical Profile & Precautions
Approved Indications & Regulatory Guidelines
Prescribing guidance, contraindications, and drug interactions for Lorazepam 2 mg tablets.
Prescription-Only Schedule H / Narcotic Medication Notice
LORZIN-2 is a Schedule H / Narcotic prescription drug. Not for OTC sale. Do not consume alcohol during therapy. Exercise caution when driving or operating machinery.
Clinical Indications Profile
Approved neurological and psychiatric indications for LORZIN-2:
- Severe Anxiety & Panic Crises: Rapid symptomatic control over intense psychic panic and tremors.
- Severe Insomnia Secondary to Anxiety: Facilitates sleep induction with restorative quality.
- Pre-Anesthetic Sedation: Produces calming and beneficial anterograde amnesia before surgery.
- Alcohol Withdrawal Agitation: Reduces tremors and acute autonomic withdrawal agitation.
Contraindications & Precautions
Key contraindications and monitoring requirements:
- Severe Respiratory Depression: Contraindicated in severe chronic obstructive pulmonary disease or sleep apnea.
- Myasthenia Gravis: Use with extreme caution due to intrinsic muscle relaxant properties.
- Alcohol Prohibition: Concurrent alcohol consumption precipitates dangerous additive CNS depression.
- Gradual Discontinuation: Taper slowly under physician direction to prevent rebound withdrawal.
Manufacturing & Marketing
Dellwich Lifescience LLPBlessme · Neuro & Psychiatric Division
About Dellwich Lifescience
Trusted Neuro & Psychiatric Pharmaceutical Manufacturer in Ahmedabad, Gujarat
Dellwich Lifescience LLP is an established pharmaceutical company based in Science City, Ahmedabad, Gujarat, dedicated to advanced formulation technology, uncompromising quality assurance, and ethical healthcare supply. Through our specialized neurology division, Blessme, we manufacture and market superior neuro-psychiatric treatments, including LORZIN-2 (Lorazepam Tablets IP 2 mg).
We support PCD pharma franchise partners, hospital supply chains, and contract manufacturing clients across India with guaranteed supply security, validated product dossiers, and prompt dispatch.
Commercial PartnershipsLORZIN-2 Supply &
LORZIN-2 Supply &
Pharmaceutical Distribution
Whether you are seeking LORZIN-2 for district monopoly PCD franchise distribution, third-party contract manufacturing, or hospital bulk procurement, Dellwich Lifescience LLP delivers dependable supply and competitive trade margins.
Exclusive Monopoly PCD Franchise
Secure district-level monopoly marketing rights for LORZIN-2 and the complete Blessme neuropsychiatry range with visual aids, product glossaries, and promotional input support.
Third-Party Contract Manufacturing
Turnkey manufacturing solutions for pharmaceutical marketing companies with flexible batch runs, rapid production turnaround, and full regulatory dossier support from Ahmedabad.
Hospital & Institutional Procurement
Direct bulk pharmaceutical supply agreements for multispecialty hospital chains, psychiatric nursing homes, and institutional medical tenders with prompt pan-India logistics.
Blessme · LORZIN-2
Why Choose LORZIN-2 Tablets?
When sourcing Lorazepam 2 mg tablets in India, LORZIN-2 by Blessme provides exceptional clinical efficacy, reliable blister packaging, and comprehensive B2B franchise support.
WHO-GMP Certified Purity
Manufactured in accredited facilities using IP grade active APIs, ensuring exact content uniformity and fast dissolution.
High-Barrier Blister Packaging
Tamper-evident, moisture-resistant blister strips protect tablets from ambient humidity and transport friction.
Pan-India Dispatch from Ahmedabad
Direct factory dispatch with GST invoicing, verified batch COA, and dependable logistics coverage across all Indian states.
Monopoly PCD Franchise Rights
Exclusive district-level franchise rights for LORZIN-2 and the Blessme portfolio with promotional visual aids.
Comprehensive Regulatory Dossiers
Certificates of Analysis (COA), stability testing data, and MSDS readily available for institutional audits and tenders.
Direct Manufacturer Support
Direct access to Dellwich Lifescience product specialists for quick quotes, customized bulk orders, and customer assistance.
Common Questions
Frequently Asked Questions about LORZIN-2
Authoritative answers to clinical, commercial, dosage, and regulatory questions regarding Lorazepam 2 mg tablets.
What is LORZIN-2 and what is it used for?
LORZIN-2 is an oral prescription tablet from the Blessme division of Dellwich Lifescience. It contains Lorazepam IP 2 mg, indicated for severe generalized anxiety, acute panic disorder, severe insomnia associated with anxiety, and pre-operative medication.
How does Lorazepam 2 mg work?
Lorazepam 2 mg enhances the action of gamma-aminobutyric acid (GABA) at the GABA_A receptor complex. This increases neuronal chloride conductance, calming acute neuronal hyper-excitation in the amygdala and cerebral cortex to extinguish intense panic and physical agitation.
When is LORZIN-2 chosen over LORZIN-1?
LORZIN-2 contains 2 mg Lorazepam, making it suitable for patients experiencing severe panic crises, debilitating anxiety unresponsive to lower doses, acute agitation, or patients requiring significant pre-procedure sedation.
How quickly does LORZIN-2 produce results?
Lorazepam is absorbed quickly from the gastrointestinal tract, achieving peak blood levels within 1.5 to 2 hours. Acute anxiolysis and sedation are typically noticeable within 30 to 45 minutes of oral intake.
What is the elimination half-life of Lorazepam 2 mg?
Lorazepam has an intermediate elimination half-life of approximately 10 to 20 hours. It is eliminated without the production of active metabolites, reducing residual hangover risks compared to long-acting benzodiazepines like Diazepam.
Does LORZIN-2 cause drowsiness?
Yes. Due to the 2 mg strength, sedation and drowsiness are prominent effects. Patients must not drive vehicles or operate hazardous equipment while taking LORZIN-2.
Can LORZIN-2 be taken with alcohol?
No. Alcohol must never be consumed while taking Lorazepam. The combination produces synergistic central nervous system depression, potentially resulting in fatal respiratory failure or profound sedation.
Is LORZIN-2 habit-forming?
Yes. Lorazepam 2 mg carries potential for physical and psychological dependence with extended therapy. It is generally prescribed for short courses (2 to 4 weeks) under direct clinical monitoring.
Can LORZIN-2 be discontinued abruptly?
No. Abrupt cessation of Lorazepam 2 mg can cause severe withdrawal reactions, including intense rebound anxiety, tremors, insomnia, and in severe cases, seizures. A supervised step-down tapering protocol is required.
Can pregnant women take LORZIN-2?
Lorazepam is contraindicated during pregnancy due to risks of congenital malformations, fetal CNS depression, and neonatal withdrawal syndrome.
How is LORZIN-2 packaged?
LORZIN-2 is packaged in 4x5x10 blister strips (200 tablets per box) with tropicalized moisture-barrier foil to ensure optimal shelf life across diverse climatic zones in India.
How can distributors apply for PCD franchise monopoly for LORZIN-2?
Pharmaceutical distributors and stockists can submit an enquiry through our online form below or contact our neuropsychiatry franchise desk at +91 99099 31992 for monopoly territory allocation.
Does Dellwich Lifescience offer third-party contract manufacturing for Lorazepam tablets?
Yes. Dellwich Lifescience provides turnkey contract manufacturing for Lorazepam oral solid dosage forms with WHO-GMP certification, validated analytical dossiers, and rapid batch dispatch.
Where is Dellwich Lifescience headquartered?
Dellwich Lifescience LLP is headquartered on Science City Road, Ahmedabad, Gujarat, India, with rapid nationwide logistics connections.
Direct Pharmaceutical Enquiry
Need Verified Information or Bulk Supply of LORZIN-2?
Connect directly with Dellwich Lifescience LLP for trade pricing, district monopoly PCD rights, third-party manufacturing, or institutional hospital tender supplies.
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Fast Dispatch from Ahmedabad with GST Invoicing
Comprehensive Marketing, Visual Aids & Promotional Inputs
Quick Assistance & Orders
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Get wholesale pricing, PCD franchise monopoly rights, and technical documentation for Lorazepam 2 mg Tablets.