01 / HIGH POTENCY ASSAY
Exact 3 mg Active Assay
Each tablet contains Lorazepam IP 3 mg with strict active assay uniformity, rapid disintegration, and dissolution complying with Indian Pharmacopoeia standards.
Blessme · Anxiolytics & Sedatives
Lorazepam Tablets IP 3 mg - LORZIN-3
LORZIN-3 is a high-strength oral neuropsychiatric formulation containing Lorazepam IP 3 mg by Blessme, Dellwich Lifescience LLP. Engineered for severe refractory generalized anxiety disorders, acute psychiatric agitation, manic restlessness, and inpatient crisis stabilization, delivering potent GABAergic limbic tranquilization via direct Phase II glucuronidation.
High-Strength 3 mg Formulation
Narcotic / Schedule H
Pan-India Supply
Product SpecificationsAbout Lorazepam Tablets IP 3 mg
About Lorazepam Tablets IP 3 mg
(LORZIN-3)
Comprehensive pharmaceutical specifications, active API monograph compliance, pharmacokinetic profiles, and 5x4x10 blister packaging details for LORZIN-3.
Blessme · Anxiolytic & Sedative
Lorazepam Tablets IP 3 mg - LORZIN-3
LORZIN-3 delivers high-potency 3 mg Lorazepam per compressed tablet. Prescribed in acute psychiatric crisis management and refractory severe anxiety where standard lower-strength regimens have failed to provide symptomatic containment.
High-Strength 3 mg Lorazepam for Inpatient & Severe Crisis Care Direct Phase II Glucuronidation (No Active Metabolites) Intermediate Half-Life (10-20 Hours) Reduces Accumulation Risk 5x4x10 Blister Strip Format for Tropical Protection Strict Indian Pharmacopoeia Quality Standards
- Product Brand Name
- LORZIN-3
- Active Pharmaceutical Ingredient
- Lorazepam IP 3 mgVerified IP
- Therapeutic Class
- Neuropsychiatric High-Strength Anxiolytic & Sedative (Benzodiazepine)
- Dosage Form
- Oral Solid Compressed Tablet
- Strength Formulation
- 3 mg Lorazepam (High-Potency Formulation)
- Packaging Standard
- 5x4x10 Blister Strips (200 Tablets per Box)
- Regulatory Category
- Narcotic Drug
- Marketing Division
- Blessme · Neuro & Psychiatric Products
- Manufacturing Standard
- WHO-GMP & ISO 9001:2015 Certified Clean-Room Compression
- Storage Condition
- Store below 25°C in a dry place. Protect from light and moisture.
- Country of Origin
- India
Clinical & Commercial MonographLorazepam Tablet 3 mg & LORZIN-3
Lorazepam Tablet 3 mg & LORZIN-3
Complete Medical & Supply Guide
In-depth pharmacological evaluation of Lorazepam 3 mg tablets, marketed as LORZIN-3 by Blessme (Dellwich Lifescience LLP). Covers GABAergic receptor mechanisms, clinical advantages of direct glucuronidation, and pharmaceutical franchise availability across India.
What is LORZIN-3 (Lorazepam 3 mg)?
LORZIN-3 is a high-potency oral benzodiazepine tablet formulated with 3 mg of pure Lorazepam IP. Engineered for clinical scenarios requiring rapid, high-magnitude GABAergic inhibition to overcome acute psychiatric distress.
In patients experiencing severe acute agitation, intractable panic attacks, or catatonic syndrome, LORZIN-3 delivers immediate suppression of autonomic panic reflexes, reducing muscle hypertonicity and terminating acute psychic turmoil.
Clinical Uses & Evidence-Based Indications
Approved neurological and psychiatric indications for LORZIN-3 include:
- Refractory Generalized Anxiety Disorder: For patients failing to stabilize on standard 1 mg or 2 mg therapies.
- Severe Acute Panic Crises: Rapidly aborts debilitating panic storms and acute agoraphobic fear.
- Acute Psychomotor Agitation: Manages manic agitation and acute psychiatric distress under clinical care.
- Catatonia: Effective oral therapy for catatonic symptoms under psychiatric supervision.
- Hospital Inpatient Sedation: Provides profound pre-procedural tranquilization in institutional settings.
Neurochemical Mechanism of Action: GABAA Receptor Positive Modulation
Lorazepam 3 mg binds with high stereospecific affinity to the allosteric benzodiazepine receptor site on the GABAA receptor complex in the central nervous system.
By enhancing the receptor’s responsiveness to gamma-aminobutyric acid (GABA), it opens neuronal chloride channels, leading to significant intracellular chloride ion influx. This causes pronounced hyperpolarization of central neurons, extinguishing extreme neuronal excitability throughout the limbic system, amygdala, and motor cortex.
High-Strength Safety Considerations
Key clinical safeguards when administering 3 mg Lorazepam:
- Individualized Titration: Initiated only when lower dosages (1 mg or 2 mg) have proven clinically inadequate.
- Direct Glucuronidation: Retains Lorazepam’s clean metabolic profile with no active metabolites despite higher strength.
- Short-Term Course: Recommended strictly for acute crisis stabilization (2 to 4 weeks) to avoid physiological dependence.
Dosage Guidelines & Administration Method
LORZIN-3 must be administered strictly under medical supervision:
- Administration: Typically 1 tablet once daily at bedtime or as directed by an attending psychiatrist.
- Swallow Whole: Take with water; do not crush or chew.
- Alcohol Prohibition: Alcohol is strictly forbidden due to fatal CNS and respiratory depression risk.
- Supervised Tapering: Must be tapered off gradually to prevent severe rebound withdrawal and seizures.
Critical Safety Warning - Schedule H / Narcotic Controlled Substance
LORZIN-3 contains high-strength Lorazepam, which carries substantial potential for dependence and habit formation with prolonged therapy. Do not consume alcohol during therapy. Not recommended during pregnancy. Dispensed strictly against a valid registered medical prescription.
Quality & Production
Pharmaceutical Quality Assurance & Compliance
LORZIN-3 is manufactured in WHO-GMP certified facilities adhering to Schedule M protocols, ensuring micro-blend homogeneity, exact active content, and superior packaging stability.
02 / PROTECTIVE PACKAGING
Tropicalized 5x4x10 Blister
High-barrier blister packaging protects against ambient humidity and photodegradation, maintaining 36-month stability across all Indian climatic zones.
03 / PHARMACOPOEIA DOSSIERS
COA & Batch Testing Records
Every batch is verified through authenticated Certificates of Analysis (COA), HPLC active assay validation, and dissolution profiles adhering strictly to IP standards.
04 / WHO-GMP COMPLIANCE
Schedule M Manufacturing
Produced in state-of-the-art cleanroom manufacturing units in Gujarat adhering to automated compression, online check-weighing, and Good Laboratory Practices (GLP).
Clinical Profile & Precautions
Approved Indications & Regulatory Guidelines
Prescribing guidance, contraindications, and drug interactions for Lorazepam 3 mg tablets.
Prescription-Only Schedule H / Narcotic Medication Notice
LORZIN-3 is a Schedule H / Narcotic prescription drug. Not for OTC sale. Do not consume alcohol during therapy. Exercise caution when driving or operating machinery.
Clinical Indications Profile
Approved neurological and psychiatric indications for LORZIN-3:
- Refractory Severe Anxiety: Controls intense autonomic panic, trembling, and hyperventilation.
- Acute Psychiatric Agitation: Manages psychomotor agitation and restlessness in inpatient settings.
- Catatonic Syndrome: Responds rapidly to high-potency Lorazepam challenge regimens.
- Inpatient Pre-Medication: Produces deep calming and anterograde amnesia prior to procedures.
Contraindications & Precautions
Key contraindications and monitoring requirements:
- Severe Respiratory Insufficiency: Contraindicated in severe COPD, acute narrow-angle glaucoma, and sleep apnea.
- Myasthenia Gravis: Use with extreme caution due to intrinsic muscle relaxant properties.
- Alcohol Prohibition: Concurrent alcohol consumption precipitates fatal respiratory failure.
- Gradual Discontinuation: Taper slowly under physician direction to prevent rebound withdrawal seizures.
Manufacturing & Marketing
Dellwich Lifescience LLPBlessme · Neuro & Psychiatric Division
About Dellwich Lifescience
Trusted Neuro & Psychiatric Pharmaceutical Manufacturer in Ahmedabad, Gujarat
Dellwich Lifescience LLP is an established pharmaceutical company based in Science City, Ahmedabad, Gujarat, dedicated to advanced formulation technology, uncompromising quality assurance, and ethical healthcare supply. Through our specialized neurology division, Blessme, we manufacture and market superior neuro-psychiatric treatments, including LORZIN-3 (Lorazepam Tablets IP 3 mg).
We support PCD pharma franchise partners, hospital supply chains, and contract manufacturing clients across India with guaranteed supply security, validated product dossiers, and prompt dispatch.
Commercial PartnershipsLORZIN-3 Supply &
LORZIN-3 Supply &
Pharmaceutical Distribution
Whether you are seeking LORZIN-3 for district monopoly PCD franchise distribution, third-party contract manufacturing, or hospital bulk procurement, Dellwich Lifescience LLP delivers dependable supply and competitive trade margins.
Exclusive Monopoly PCD Franchise
Secure district-level monopoly marketing rights for LORZIN-3 and the complete Blessme neuropsychiatry range with visual aids, product glossaries, and promotional input support.
Third-Party Contract Manufacturing
Turnkey manufacturing solutions for pharmaceutical marketing companies with flexible batch runs, rapid production turnaround, and full regulatory dossier support from Ahmedabad.
Hospital & Institutional Procurement
Direct bulk pharmaceutical supply agreements for multispecialty hospital chains, psychiatric nursing homes, and institutional medical tenders with prompt pan-India logistics.
Blessme · LORZIN-3
Why Choose LORZIN-3 Tablets?
When sourcing Lorazepam 3 mg tablets in India, LORZIN-3 by Blessme provides exceptional clinical efficacy, reliable blister packaging, and comprehensive B2B franchise support.
WHO-GMP Certified Purity
Manufactured in accredited facilities using IP grade active APIs, ensuring exact content uniformity and fast dissolution.
High-Barrier Blister Packaging
Tamper-evident, moisture-resistant blister strips protect tablets from ambient humidity and transport friction.
Pan-India Dispatch from Ahmedabad
Direct factory dispatch with GST invoicing, verified batch COA, and dependable logistics coverage across all Indian states.
Monopoly PCD Franchise Rights
Exclusive district-level franchise rights for LORZIN-3 and the Blessme portfolio with promotional visual aids.
Comprehensive Regulatory Dossiers
Certificates of Analysis (COA), stability testing data, and MSDS readily available for institutional audits and tenders.
Direct Manufacturer Support
Direct access to Dellwich Lifescience product specialists for quick quotes, customized bulk orders, and customer assistance.
Common Questions
Frequently Asked Questions about LORZIN-3
Authoritative answers to clinical, commercial, dosage, and regulatory questions regarding Lorazepam 3 mg tablets.
What is LORZIN-3 and what does it contain?
LORZIN-3 is a high-strength oral prescription tablet from the Blessme division of Dellwich Lifescience. It contains Lorazepam IP 3 mg, indicated for severe refractory anxiety, acute psychiatric agitation, and inpatient neuropsychiatric crisis management.
When is LORZIN-3 prescribed instead of lower strengths?
LORZIN-3 delivers 3 mg Lorazepam in a single unit dose. It is reserved for severe acute anxiety, profound psychomotor excitement, catatonic states, or patients who have developed tolerance to lower benzodiazepine dosages under psychiatric supervision.
How does Lorazepam 3 mg work in the central nervous system?
Lorazepam 3 mg exerts potent positive allosteric modulation at GABA_A receptors. By amplifying inhibitory chloride channel opening, it causes strong hyperpolarization of central neurons, terminating intense panic, agitation, and psychic frenzy.
What is the elimination half-life of Lorazepam 3 mg?
Lorazepam has an intermediate elimination half-life of 10 to 20 hours. Because it undergoes simple direct glucuronidation without active metabolites, it does not accumulate to the same degree as long-acting agents like Diazepam.
Does LORZIN-3 cause strong sedation?
Yes. Due to the 3 mg strength, significant sedation, muscular relaxation, and drowsiness are expected. Patients must avoid driving or performing any tasks requiring mental alertness.
Can LORZIN-3 be taken with alcohol?
No. Alcohol is strictly contraindicated. Combining high-dose Lorazepam with alcohol can lead to life-threatening respiratory depression, profound coma, and cardiovascular collapse.
Is LORZIN-3 habit-forming?
Yes. The 3 mg formulation carries high risk of psychological and physiological dependence with extended use. It should be used for short durations under stringent psychiatric monitoring.
Can LORZIN-3 be discontinued abruptly?
No. Abrupt stoppage from 3 mg Lorazepam can trigger severe withdrawal phenomena, including severe rebound agitation, tremors, insomnia, delirium, and seizures. A gradual, medically supervised step-down tapering regimen is mandatory.
Can pregnant women take LORZIN-3?
LORZIN-3 is strictly contraindicated during pregnancy due to the risk of fetal malformations, hypotonia, and neonatal withdrawal syndrome.
How is LORZIN-3 packaged?
LORZIN-3 is supplied in 5x4x10 blister strips (200 tablets per box) with tropicalized high-barrier foil to ensure stability against humidity and temperature variations across India.
How can distributors apply for PCD franchise monopoly for LORZIN-3?
Pharmaceutical distributors and stockists can submit an enquiry through our online form below or contact our neuropsychiatry franchise desk at +91 99099 31992 for monopoly territory allocation.
Does Dellwich Lifescience offer third-party contract manufacturing for Lorazepam tablets?
Yes. Dellwich Lifescience provides turnkey contract manufacturing for Lorazepam oral solid dosage forms with WHO-GMP certification, validated analytical dossiers, and rapid batch dispatch.
Where is Dellwich Lifescience headquartered?
Dellwich Lifescience LLP is headquartered on Science City Road, Ahmedabad, Gujarat, India, with rapid nationwide logistics connections.
Direct Pharmaceutical Enquiry
Need Verified Information or Bulk Supply of LORZIN-3?
Connect directly with Dellwich Lifescience LLP for trade pricing, district monopoly PCD rights, third-party manufacturing, or institutional hospital tender supplies.
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Exclusive PCD Monopoly Rights for Designated Districts
Fast Dispatch from Ahmedabad with GST Invoicing
Comprehensive Marketing, Visual Aids & Promotional Inputs
Quick Assistance & Orders
Enquire About LORZIN-3
Get wholesale pricing, PCD franchise monopoly rights, and technical documentation for Lorazepam 3 mg Tablets.