An Alprazolam Propranolol HCl tablet is a prescription fixed-dose combination of Alprazolam (0.25 mg) and Propranolol Hydrochloride (20 mg). It is used to treat anxiety disorders with prominent physical symptoms-such as palpitations, trembling, and rapid heartbeat. Propranolol also has an established role in migraine prevention. This page explains the generic alprazolam propranolol HCl tablet in detail and also provides authentic manufacturer information for MIGABET-PLUS, the WHO-GMP brand produced by Dellwich Lifescience LLP.
An Alprazolam Propranolol HCl tablet combines a benzodiazepine with a beta-blocker in a single dose. The standard composition is Alprazolam 0.25 mg and Propranolol Hydrochloride 20 mg. Because it contains alprazolam, it is a Schedule H1, prescription-only medicine in India.
This Alprazolam Propranolol HCl tablet is designed to address both the mental and physical dimensions of anxiety. Alprazolam reduces excessive worry and fear, while Propranolol controls the adrenaline-driven somatic symptoms that accompany panic and stress.
A reference overview of the generic Alprazolam Propranolol HCl tablet combination, including how it works, what it treats, common adverse effects, and critical safety warnings. This information is for educational purposes and does not replace medical advice.
The combination is prescribed for anxiety disorders and related somatic symptoms. Key uses include:
Alprazolam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger that suppresses abnormal and excessive activity of nerve cells in the brain. This produces a calming effect on psychic anxiety.
Propranolol HCl is a beta-blocker. It blocks the action of certain chemical messengers on the heart and blood vessels, reducing heart rate, blood pressure, and strain on the heart. In anxiety, it counteracts adrenaline effects that cause rapid heartbeat, trembling, and elevated blood pressure.
Together, the two medicines in the Alprazolam Propranolol HCl tablet provide dual relief: Alprazolam calms the mind, while Propranolol stabilizes the body's physical stress response.
Most side effects are mild and tend to diminish as the body adjusts. However, patients should report persistent or bothersome symptoms to their doctor. Commonly reported effects include:
Serious side effects are rare but require immediate medical attention. These include extreme drowsiness, difficulty breathing, irregular heartbeat, fainting, or signs of a severe allergic reaction such as rash or swelling.
Alprazolam Propranolol HCl tablets contain Alprazolam, a benzodiazepine with a risk of dependence and withdrawal. Do not consume alcohol during therapy. Do not use with opioid medicines unless your doctor specifically advises it, as the combination can cause profound sedation and breathing depression. Do not drive or operate machinery until you know how the medicine affects you. Never stop treatment abruptly-taper under medical supervision to avoid rebound anxiety, insomnia, and cardiovascular effects. This medicine must be dispensed only against a valid prescription.
Published by Dellwich Lifescience LLP. Last updated .
The generic Alprazolam Propranolol HCl tablet is manufactured by multiple companies. MIGABET-PLUS, produced by Dellwich Lifescience LLP, follows WHO-GMP and Schedule M protocols to ensure consistent quality and stability.
In the Alprazolam Propranolol HCl tablet, Alprazolam targets GABA_A receptors in the brain to reduce psychic anxiety, while Propranolol blocks beta-adrenergic receptors to control palpitations, tremors, and tachycardia.
Each tablet is sealed in high-barrier blister packaging to protect the active pharmaceutical ingredients from humidity and light degradation during transport and storage.
Every batch of Alprazolam Propranolol HCl tablets is tested for assay, uniformity of content, and dissolution profile in accordance with Indian Pharmacopoeia standards.
Produced in WHO-GMP certified facilities following Schedule M requirements, with online quality checks during compression and packaging.
In India, the Alprazolam Propranolol HCl tablet is regulated as a Schedule H1 drug. It cannot be purchased over the counter.
Alprazolam is a psychotropic substance and Schedule H1 drug; sale requires a valid prescription and is recorded by the pharmacy. Dispensing without a prescription is illegal. The combination is intended for supervised, short-term use. Long-term use requires periodic reassessment by the prescribing physician.
Alprazolam and Propranolol can interact with other medicines. Inform your doctor if you are taking:
MIGABET-PLUS is the registered brand of the generic Alprazolam Propranolol HCl tablet manufactured by Dellwich Lifescience LLP, Ahmedabad. It contains Alprazolam IP 0.25 mg and Propranolol Hydrochloride IP 20 mg, the same active ingredients and strengths described throughout this guide.
Dellwich Lifescience LLP is a WHO-GMP and ISO 9001:2015 certified pharmaceutical manufacturer based in Science City, Ahmedabad, Gujarat. The company specializes in neurology and psychiatry formulations through its Blessme division and supplies MIGABET-PLUS to hospitals, distributors, and PCD franchise partners across India.
Dellwich Lifescience LLP provides commercial access to MIGABET-PLUS for distributors, hospitals, and contract manufacturing clients.
District-level monopoly marketing rights for MIGABET-PLUS (Alprazolam Propranolol HCl tablet) with visual aids, promotional support, and a defined territory.
Contract manufacturing of Alprazolam Propranolol HCl tablets for other marketing companies, with flexible batch sizes and regulatory dossier support from Ahmedabad.
Bulk supply agreements for hospitals, psychiatric clinics, and institutional tenders with pan-India logistics and GST-compliant invoicing.
Several brands of the Alprazolam Propranolol HCl tablet are available in India. MIGABET-PLUS differentiates itself through manufacturing rigor, packaging quality, and direct manufacturer accessibility.
Produced in accredited facilities using IP-grade active ingredients, with batch-level certificates of analysis.
Moisture-resistant blister strips protect tablet integrity during transport and storage in Indian climatic conditions.
Pan-India dispatch from Ahmedabad with GST invoicing and verified batch documentation.
Monopoly territory rights for distributors, supported by promotional visual aids and product literature.
COA, stability data, and MSDS available for institutional procurement and tender submissions.
Speak directly with Dellwich Lifescience for pricing, batch availability, and partnership discussions.
Answers to common questions about uses, side effects, dosage, safety, and brands of the Alprazolam Propranolol HCl tablet.
An Alprazolam Propranolol HCl tablet is primarily used to treat anxiety disorders, including generalized anxiety and panic attacks. Alprazolam calms the brain by enhancing GABA, while Propranolol reduces the physical symptoms of anxiety such as rapid heartbeat, trembling, and high blood pressure by blocking adrenaline. Propranolol has an established role in migraine prevention; whether the combination is suitable for stress-related migraine is a decision for the prescribing doctor.
Common side effects include confusion, drowsiness, memory impairment, slow heart rate, tiredness, uncoordinated body movements, nightmares, and cold extremities. Most effects are mild and temporary, but persistent or severe symptoms should be reported to a doctor.
Alprazolam is a benzodiazepine that increases the action of GABA, suppressing abnormal nerve cell activity in the brain. Propranolol is a beta blocker that blocks chemical messengers acting on the heart and blood vessels, reducing heart rate, blood pressure, and cardiac strain. Together, they address both the psychological and physical symptoms of anxiety.
The tablet is contraindicated in people allergic to either component, those with asthma or breathing problems, a very low heart rate, severe heart failure, cardiogenic shock, glaucoma, or muscle disorders like myasthenia gravis.
Dosage is determined by the prescribing physician. A typical strength is Alprazolam 0.25 mg with Propranolol HCl 20 mg. It is usually taken as directed, often once or twice daily. The tablet should be swallowed whole with water and never chewed or crushed.
No. Abrupt discontinuation can cause rebound anxiety, insomnia, and withdrawal symptoms from Alprazolam, as well as rebound tachycardia and blood pressure spikes from Propranolol. A gradual tapering schedule under medical supervision is essential.
No. Alcohol interacts dangerously with both components. It enhances the sedative effect of Alprazolam and the blood-pressure-lowering effect of Propranolol, causing excessive drowsiness, dizziness, and risk of fainting.
Several brands are available, including MIGABET-PLUS manufactured by Dellwich Lifescience LLP under the Blessme division. MIGABET-PLUS contains Alprazolam IP 0.25 mg and Propranolol Hydrochloride IP 20 mg in a WHO-GMP certified formulation.
Elderly patients should use the combination with caution because they may be more sensitive to side effects such as dizziness, confusion, and low blood pressure. Close medical monitoring is recommended.
It is generally prescribed for short-term management of anxiety symptoms. Prolonged use increases the risk of dependence and side effects. Regular follow-up with the doctor is necessary to adjust or safely stop treatment.
This combination is generally avoided during pregnancy and breastfeeding unless the doctor determines the benefit outweighs the risk. Both Alprazolam and Propranolol can pass into breast milk and may affect the baby. Medical advice is essential.
Yes. MIGABET-PLUS is a brand of the Alprazolam Propranolol HCl tablet manufactured by Dellwich Lifescience LLP. It contains Alprazolam IP 0.25 mg and Propranolol Hydrochloride IP 20 mg, the same active ingredients found in other branded versions of this combination.
Contact Dellwich Lifescience LLP for trade pricing, PCD franchise allocation, third-party manufacturing, or institutional supply of MIGABET-PLUS.
Get wholesale pricing, PCD franchise monopoly rights, and technical documentation for Propranolol 20 mg + Alprazolam 0.25 mg Tablets.